Overviewoverview endocrine system composed of hormonereleasing organs such as the. Pth acts on bone, the kidneys, and the gi tract to increase calcium reabsorption and phosphate excretion. There are many drugs that can be used to influence the endocrine system. Several synthetic steroids and hormonally active substances are able to affect the endocrine system. Oxytocin and vasopressin are produced in the posterior pituitary an outgrowth of the hypothalamus where they are released into general circulation. A plethora of hormones regulate many of the bodys functions, including growth and development, metabolism, electrolyte. Erythropoietin is produced when oxygen levels in the blood are low.
Endocrine drugs, hormones andendocrine drugs, hormones and related compoundsrelated compounds 2. Drugs affecting the endocrine system pharmacology thyroid. Both the nervous system and endocrine system perform this function in higher animals. The nervous system acts by using a rapid, short lived response while the endocrine system produces a slow, longer response. Adrenal hormones glucocorticoids mechanism of action. Hypothalamic hormones regulate the release of anterior pituitary hormones. Neuroendocrine system gland found in the sella turcica of the brain. Hormones are chemicals which circulate through the blood sometimes special ducts and control the workings of organs and tissues in the body. Similarly, fsh acts on sertoli cells to drive the secretion of a protein hormone, inhibin b, which then travels via the bloodstream to the pituitary gland to suppress. Communicating within the body 63 the evolutionary foundations of the nervous system the complexities of the nervous system can be better understood if we take the course of evolution into consideration. The endocrine system is a chemical messenger system comprising feedback loops of the.
Evaluate changes in weight, particularly increase in weight in the adult and decrease in weight in the child. All the endocrine agents listed below are peptides, except for prolactininhibiting hormone. The endocrine system secretes these substances inside the body to regulate metabolism, fertility, the fightorflight response, and cell growth, among other responsibilities. Evaluate reflexes and neuromuscular response to stimuli. When an electrical signal in the form of an action potential arrives at the synaptic terminal, they diffuse across the synaptic. Here is a rundown of the endocrines glands that form this system and their functions.
Module 6 the nervous system and the endocrine system. Insulin lispro humalog rapid acting within 15 min regular insulin humulin short, subq, iv only insulin that can be given iv insulin isophane nph intermediate. Hormone circulates in blood and acts at target organs where hormone receptor. Medications affecting the endocrine system part 1diabetes mellitus objectives. Hormones act on nearby tissues or are carried in the bloodstream to act on specific target organs and distant tissues. Course hero has thousands of endocrine system study resources to help you. They do not have ducts and hence they are called as ductless glands. Objectives discuss the physiologic effects of insulin on carbohydrate, lipid, and protein metabolism, and identify those body cellstissues that most depend on insulin for providing glucose as the main metabolic fuel. Organs which are affected by a hormone are called target organs. Drugs used to treat endocrine disorders pharmacology. Pharmacology of the endocrine system proprofs quiz. Neurohormones synthesized in the hypothalamus reach the anterior pituitary adenohypophysis through a specialized portal vascular system and regulate synthesis and release of the 6 major peptide hormones of the anterior pituitary see figure the pituitary and its target organs. A plethora of hormones regulate many of the bodys functions, including growth and development, metabolism, electrolyte balances, and reproduction.
The hypothalamus serves as the interface between the nervous system and the endocrine system, and it controls the secretions of the pituitary. Endocrine system drugs created by the njardarson group the university of arizona. Chemicals secreted by the glands of this system have effects on numerous organs of multiple systems and control or regulate various mechanisms of every other body system the major endocrine glands. Sweat glands, saliva, and mammary glands are all parts of the exocrine system. It does not include exocrine glands such as salivary glands, sweat glands and glands within the gastrointestinal tract subcategories. Endocrine system is a series of organs and glands in your body that secret chemical messengers called hormones in to your blood stream.
This chapter describes drugs used for hormonal replacement and for inhibition of hormonal secretion from the pituitary, thyroid, parathyroid, and adrenal glands. The endocrine system consists of a series of glands that produce chemical substances known as hormones. Drugs acting on the endocrine system ali jaber, ph. In fact the hypothalamus, a part of the nervous system, and the pituitary gland, a. Of course, you want relief from your anxiety and you can get that since anxiety is incredibly treatable but what you do not want to do is stop this system from occurring in general, because its an extremely important system for. The endocrine system works with the nervous system to regulate and integrate the processes of the body such as growth, development, reproduction, response to stress, and change of food into energy and body tissue. Chemicals secreted by the glands of this system have effects on numerous organs of multiple systems and control or regulate various mechanisms of every other body system. Home explore pharmacology drugs acting on endocrine system. Consider the thyroid gland, an important part of this system. The endocrine system consists of a collection of glands that regulate a number of vital functions of our body.
All of these glands coordinate with each other in order to regulate various life processes. Drugs acting on the endocrine system flashcards quizlet. Find endocrine system course notes, answered questions, and endocrine system tutors 247. System nursing 3703 pharmacology by linda self hypothalamic, pituitary, parathyroid, and adrenal hormones hypothalamus secretes releasing hormones affecting both the anterior and posterior pituitary posterior pituitary secretes adh and oxytocinadh conserves water, oxytocin functions in childbirth and lactation anterior pituitary hormones and target tissues 1. Treatment and management of common endocrine disorders. The presence of functioning tumours in more than one endocrine gland, commonly the pancreatic islets and parathyroid glands, which may be associated with zollingerellison syndrome. The glands of the endocrine system secrete hormones to regulate normal body functions.
Insulin lispro humalog, insulin aspart novolog, insulin glulisin apidra 0. Overview of the endocrine system endocrine and metabolic. Testing the functional integration of an endocrine system diagnostic. However, unlike neurotransmitters, which are released in close proximity to cells with their receptors, hormones are secreted. Objectives discuss the physiologic effects of insulin on carbohydrate, lipid, and protein metabolism, and identify those body cellstissues that most depend on insulin. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Treatment and management of common endocrine disorders open. The endocrine system is a control system of ductless endocrine glands that secrete chemical messengers called hormones that circulate within the body via the bloodstream to affect distant organs. Endocrinology relationships between the endocrine and. Currently there are 3 recognized classes of injectable antihyperglycemics.
Describe the common characteristics and functions of hormones. Drugs acting on the endocrine system hypothalamic and pituitary agents pharmacokinetics for the most part, these drugs are absorbed slowly when given intramuscularly im, subcutaneously, or in depot form. By mary green the endocrine system consists of a collection of glands that regulate a number of vital functions of our body. Datye, md, is a pgy3 resident in pediatrics, vanderbilt university school of medicine. Inhibits osteoclast activity, reduces bone reabsorption. Endocrine, thyroid, molecular diagnosis, graves disease, diabetes. Landis nobody can go back and start a new beginning, but anyone can start today and make a new ending. Pharmacology of the endocrine system 2 in clinical practice, hormones and hormonelike drugs, are mainly used for. The endocrine system national institute on alcohol abuse and. The impact of opioids on the endocrine system request pdf. Endocrine glands are the glands of endocrine system which normally secrete special products called hormones directly into the blood 14. Questions on diabetes type 1 and 2, adh insufficiency, adrenal disorders, thyroid disorders, reproductive treatments, and more. Drugs acting on the endocrine system is the property of its rightful owner.
Somatostatin is released by delta cells and acts as an inhibitor of gh, insulin and glucagon. It does not include exocrine glands such as salivary glands, sweat glands and glands within the gastrointestinal tract. Chapter 48 nursing assessment endocrine system susan c. Review common endocrine conditions that often present in the newborn and perinatal period.
Endocrine glands are ductless glands of the endocrine system that secrete their products. What drugs can cause complications endocrine exocrine. Adrenal hormones glucocorticoids mechanism of action, therapeutic uses and adverse effects. Endocrine glands send chemical signal molecules around the body to communicate information. This category has the following 18 subcategories, out of 18 total.
The two systems work together like a giant super system. Apr 29, 2008 comparison of insulin peak action 1020 hrs 48 hrs ultralente long acting 68 hrs to 12 hrs 1. In such cases, the substance may possess inherent hormonal activity and therefore act rather specifically on a particular target organ of the endocrine system. If so, share your ppt presentation slides online with. In addition, pth stimulates the conversion of vitamin. The multiple consequences of smoking, which reflect the endocrine system, depend on many factors, as the mode of tobacco consumption, on intensity of smoking, the duration of the addiction, on the. Data sources include ibm watson micromedex updated 4 may 2020, cerner multum updated 4 may 2020, wolters kluwer updated. The pituitary serves as the master gland, controlling the secretions of all other glands. They tend to have very long halflives of days to weeks, metabolism is not. Medications affecting the endocrine syst authorstream.
The endocrine system maintenance of internal homeostasis through the secretion of hormones endocrine glands make and release these endogenous substances to regulate. The way the endocrine system works is by releasing chemical messengers called hormones into the blood. It acts in bone marrow to stimulate the production of mature red blood cells and to maintain. Ppt drugs acting on the endocrine system powerpoint.
This drug combats acromegaly by acting as somatostain, a growth hormone release inhibiting factor. Drugs acting on the endocrine system thyroid glands. More endocrine system quizzes learn about endocrine system quiz. To this day we have a serious lack of data in regards to this topic despite the fact that opioids both endogenous and exogenousevidently affect the endocrine system katz and mazer, 2009. Drugs affecting the endocrine system lange smart charts. Together with the nervous system, it is considered one the two long distance control systems of the body. Drugs acting on the endocrine system by kathrine kaye. The exocrine system works similarly, but secretes substances outside the body. Like neurotransmitters, hormones are chemical messengers that must bind to a receptor in order to send their signal. Effects of drugs on the endocrine system springerlink. These anterior pituitary hormones regulate peripheral endocrine glands the thyroid, adrenals, and gonads as well as growth and lactation.
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